I think a sasquatch could take anyone if it wanted to by means of a surprise attack. Having said, I would feel comfortable that a big bore revolver, or brush gun, could take down one if the need arose. I carry a 454 Casull with 360gr hard-cast flat-nose bullets and am confident I could defend myself with it from an assault where I have a shot at one.
I am with you on that. I carry a weapon but realized after my first encounter it would be little use stopping a BF. Probably just enrage it. So I keep the use of the weapon reserved for bear, cougar, and myself should I tick off a BF enough to not kill me outright. Disembowelment is a particularly nasty way to suffer and die.