Who to trust is a big problem. If there is a conspiracy to suppress evidence, every lab capable of doing the DNA testing has to already be compromised. About the only thing I can think of to do is send parts of the same larger sample to multiple labs, without telling them others are testing and especially without telling them who those others are, and then see if the results come back the same or not. If it were me, I would deliberately include labs I thought were compromised and hope to use the others' results to verify or falsify my assumption about the questionable labs. Costs a lot of money to do that though. Might be able to pull it off, might not, but I would not even try, and certainly would not ask others for a loan, unless I was __absolutely__ sure of the DNA source.
My sense is, as I tried to say before, that bigfoot is so close to human that without a bigfoot type sample we are sure of, there's no way a test .. e-DNA or other .. meant for species identification is going to return any result but human .. possibly degraded, but human. Those tests for neanderthal or denisovan ... they are done on samples that they strongly suspect are not precisely H. sapiens sapiens. It's not the same test done to see if a bone found in the environment is human vs raccoon vs some known protected species.
One thing they can look at is the number of chromosomes pairs in the gene. If bigfoot is closer to African apes they may well have 24 or more. If they are closer to us, they may share 23 with us. So one interesting test would be for apparent primate DNA in north america with 24 or more chromosome pairs, but it only works if bigfoot is farther from us than I think they are.
FWIW, I think Sykes was mis-quoted above. Zana's DNA is clearly human but it lacks some of the mutations found in modern African populations. This means her ancestors left Africa before those mutations occurred. The rate of mutation is fairly steady, a sort of clock. That seems to put her ancestors' exit from Africa quite a bit before the current out-of-Africa theory suggests anyone left. We're seeing that that assumption is coming into ever greater question. Zana is just one more hole in the armor.
MIB